PhytophthoraV1, Main, Exploration, bibRecord, 000806

Design, Synthesis, and Antifungal Activities of Novel 1,2,4-Triazole Schiff Base Derivatives.

Identifieur interne : 000806 ( Main/Exploration ); précédent : 000805; suivant : 000807

Design, Synthesis, and Antifungal Activities of Novel 1,2,4-Triazole Schiff Base Derivatives.

Auteurs : Ruyi Jin [République populaire de Chine] ; Jingli Liu [République populaire de Chine] ; Guanghui Zhang [République populaire de Chine] ; Jiajia Li [République populaire de Chine] ; Shuan Zhang [République populaire de Chine] ; Hui Guo [République populaire de Chine]

Source :

Chemistry & biodiversity [ 1612-1880 ] ; 2018.

RBID : pubmed:29981528

Descripteurs français

KwdFr :
- Antifongiques (composition chimique), Antifongiques (pharmacologie), Antifongiques (synthèse chimique), Bases de Schiff (composition chimique), Champignons (classification), Champignons (effets des médicaments et des substances chimiques), Conception de médicament (MeSH), Tests de sensibilité microbienne (MeSH), Triazoles (composition chimique), Triazoles (pharmacologie), Triazoles (synthèse chimique).
MESH :
- composition chimique : Antifongiques, Bases de Schiff, Champignons, Triazoles.
- effets des médicaments et des substances chimiques : Champignons.
- pharmacologie : Antifongiques, Triazoles.
- synthèse chimique : Antifongiques, Triazoles.
- Conception de médicament, Tests de sensibilité microbienne.

English descriptors

KwdEn :
- Antifungal Agents (chemical synthesis), Antifungal Agents (chemistry), Antifungal Agents (pharmacology), Drug Design (MeSH), Fungi (classification), Fungi (drug effects), Microbial Sensitivity Tests (MeSH), Schiff Bases (chemistry), Triazoles (chemical synthesis), Triazoles (chemistry), Triazoles (pharmacology).
MESH :
- chemical , chemical synthesis : Antifungal Agents, Triazoles.
- chemical , chemistry : Antifungal Agents, Schiff Bases, Triazoles.
- chemical , pharmacology : Antifungal Agents, Triazoles.
- classification : Fungi.
- drug effects : Fungi.
- Drug Design, Microbial Sensitivity Tests.

Abstract

With the aim to find new compounds with high antifungal activity, 21 4-amino-5-substituted-1,2,4-triazole Schiff bases (2a - 2g, 3a - 3g, and 4a - 4g) were designed and synthesized. Their antifungal activities against Pythium solani, Gibberlla nicotiancola, Fusarium oxysporium f. sp. niveum, Gibberlla saubinetii, Alternaria iycopersici, Phytophthora capsici, Physalospora piricola, Cercospora arachidicola hori, and Fusarium oxysporium f. sp. cucumber were tested, parts of the compounds exhibited excellent antifungal activity. This research provides useful information for further study of antifungal agents.

DOI: 10.1002/cbdv.201800263
PubMed: 29981528

Affiliations:

République populaire de Chine

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000718
to stream Main, to step Curation: 000718

Le document en format XML

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<term>Fungi (classification)</term>
<term>Fungi (drug effects)</term>
<term>Microbial Sensitivity Tests (MeSH)</term>
<term>Schiff Bases (chemistry)</term>
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<term>Conception de médicament (MeSH)</term>
<term>Tests de sensibilité microbienne (MeSH)</term>
<term>Triazoles (composition chimique)</term>
<term>Triazoles (pharmacologie)</term>
<term>Triazoles (synthèse chimique)</term>
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<front><div type="abstract" xml:lang="en">With the aim to find new compounds with high antifungal activity, 21 4-amino-5-substituted-1,2,4-triazole Schiff bases (2a - 2g, 3a - 3g, and 4a - 4g) were designed and synthesized. Their antifungal activities against Pythium solani, Gibberlla nicotiancola, Fusarium oxysporium f. sp. niveum, Gibberlla saubinetii, Alternaria iycopersici, Phytophthora capsici, Physalospora piricola, Cercospora arachidicola hori, and Fusarium oxysporium f. sp. cucumber were tested, parts of the compounds exhibited excellent antifungal activity. This research provides useful information for further study of antifungal agents.</div>
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	Serveur d'exploration Phytophthora
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Serveur d'exploration Phytophthora

Design, Synthesis, and Antifungal Activities of Novel 1,2,4-Triazole Schiff Base Derivatives.

Design, Synthesis, and Antifungal Activities of Novel 1,2,4-Triazole Schiff Base Derivatives.

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